A traditional Chinese medicine composition has a significant effect on a specific type of leukemia super bass

A traditional Chinese medicine composition for leukemia specific type of significant – Beijing, a traditional Chinese medicine composition for a specific type of leukemia was 8 October, Xinhua news agency, Washington (reporter Lin Xiaochun) a China from University of Hong Kong led international research team in the new issue of the United States "Science Translational Medicine" magazine report, made from three Chinese Cephalotaxus fortunei in the genus homoharringtonine, used in the treatment of patients with acute myeloid leukemia FLT3ITD gene mutations of the remarkable curative effect. Acute myeloid leukemia is the most common form of cancer in adult blood system, nearly 30% of the patients with acute myeloid leukemia with FLT3ITD gene mutation. Liang Ruhong, vice president of Medical College of University of Hong Kong participated in the study China Li Jiacheng told Xinhua that the standard chemotherapy and drug Sola Feeney is not ideal for patients with acute myeloid leukemia carrying this mutation. In order to find a better method of treatment, they used the patient’s leukemia cells in vitro drug screening, found that the inhibitory effect of huperzine a. According to Liang Ruhong introduction, the base of the high grade is extracted from three species of plants in the genus alkali. In China, the use of high – grade alkali is commonly used in the treatment of acute myeloid leukemia, but not for a specific type of leukemia, so the effect is not significant. Liang Ruhong has recruited 24 patients with relapsed or refractory acute myeloid leukemia with FLT3 gene mutation of ITD in clinical trials, the use of homoharringtonine and Sola Feeney combined treatment results of 20 patients in the leukemia cells are removed, the overall survival was significantly prolonged. Liang Ruhong said that the base can inhibit cell protein synthesis, so that cancer cells can not produce important protein, leading to cancer cell apoptosis. "Relative to existing method, small side effects of combination therapy, can be applied to the frail or elderly patients," Liang Ruhong believes that this study provides an effective treatment strategy for FLT3 ITD in acute myeloid leukemia.相关的主题文章: